An efficient synthesis of trisubstituted oxazoles via chemoselective O-acylations and intramolecular Wittig reactions.
نویسندگان
چکیده
Preparation of new types of trisubstituted oxazoles is realized via chemoselective O-acylations and intramolecular Wittig reactions with ester functionalities using in situ formed phosphorus ylides as key intermediates. A plausible reaction mechanism for this undiscovered chemistry is also proposed based on the existence of expected and rearranged isomeric oxazoles.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 87 شماره
صفحات -
تاریخ انتشار 2013